Study reveals genetic mechanism behind Tibetans' high
Time:2024-05-21 12:04:45 Source:healthViews(143)
BEIJING, Sept. 5 (Xinhua) -- Chinese scientists have identified the genetic mechanism that allows Tibetans to maintain a high level of reproductive health in an oxygen-deficient highland environment.
Conducted by researchers from the Kunming Institute of Zoology (KIZ) under the Chinese Academy of Sciences, the study was published recently in the journal Current Biology.
According to the study, "The adaptation of Tibetans to high-altitude environments has been studied extensively. However, the direct assessment of evolutionary adaptation, i.e., the reproductive fitness of Tibetans and its genetic basis, remains elusive."
In order to identify a genetic basis for their good reproductive health at high altitudes, the researchers conducted systematic phenotyping and genome-wide association analysis of 2,252 mother-newborn pairs of indigenous Tibetans, covering 12 reproductive traits and 76 maternal physiological traits.
They found that, compared with the lowland immigrants living at high altitudes, indigenous Tibetans show better reproductive outcomes, reflected in their lower abortion rate, higher birth weight and better fetal development.
According to the study, the results of genome-wide association analyses indicate a polygenic adaptation of reproduction in Tibetans, attributed to the genomic backgrounds of both the mothers and the newborns.
"Collectively, these results shed new light on the phenotypic pattern and the genetic mechanism of human reproductive fitness in extreme environments," said He Yaoxi, the corresponding author of the study and a researcher at KIZ.
The study will provide important points of reference for highland medicine and physiology, He added.
Previous:Pope trip to Luxembourg, Belgium confirmed for September, 2 weeks after challenging Asia visit
Next:The Latest
You may also like
- Who is Jacob Zuma, the former South African president disqualified from next week's election?
- Revealed: Erotic fantasies of Slovakia Prime Minister's would
- The one American city that's almost beaten the war on inflation
- 2 workers die after buried alive in well in Philippines
- Supreme Court rejects an appeal from a Canadian man once held at Guantanamo
- Over 4,000 species affected by wildlife trafficking: UN report
- Visitors flock to celebrate Hong Kong's unique Bun Festival
- South Africa elections 2024: What you need to know
- California congressman urges closer consultation with tribes on offshore wind